Treatment & Safety
Naltrexone Contraindications: Opioids, Withdrawal, and Label Checks
Current opioid use, opioid dependence, acute withdrawal, specified test results, and prior hypersensitivity can make naltrexone unsafe to start.
4 minute read
Naltrexone Guides
Plain-language answers to the questions that come up before treatment, from recent opioid use and side effects to cost and country access.
Latest guides
Treatment & Safety
Starting Naltrexone After Opioids: Why the Opioid-Free Interval Matters
Naltrexone can trigger severe withdrawal if opioids are still present. The minimum interval is not a self-assessment rule and may be longer after buprenorphine or methadone.
4 minute read
Treatment & Safety
Naltrexone Side Effects: Expected Effects and Urgent Safety Signals
Nausea, headache, dizziness, and tiredness are reported with naltrexone. Vivitrol also has injection-site effects; certain symptoms need prompt clinical review.
4 minute read
Treatment & Safety
Vivitrol Injection Administration: What Patients Should Know
Vivitrol is prepared and given only by a healthcare provider as a deep gluteal injection. This guide explains the patient-facing safety essentials.
4 minute read
Access by Country
Australia Naltrexone PBS Check: Item 8370M and 2026 Co-payments
PBS item 8370M covers naltrexone 50 mg tablets; 2026 maximum co-payments are $25 general and $7.70 concession.
2 minute read
Treatment & Safety
Naltrexone and Liver Disease: What Current Evidence Shows
Observational studies are reassuring in many patients with liver disease and cirrhosis, but they do not make naltrexone risk-free or settle every decompensated-liver scenario.
3 minute read
Access by Country
New Zealand Naltrexone Funding: June 2026 PHARMAC Check
Naltraccord 50 mg is fully subsidised under SA1408, while pharmacy charges and GP fees remain separate.
2 minute read
Treatment & Safety
Naltrexone During Pregnancy and Breastfeeding: What We Know
Human pregnancy evidence remains limited; breastfeeding transfer appears low in one published case. Decisions require individual specialist assessment.
3 minute read
Access by Country
Singapore Naltrexone Check: Contrave Is Registered—What About 50 mg?
Singapore's official formulary confirms Contrave, while current standalone 50 mg naltrexone supply and price remain unverified.
2 minute read
Access by Country
UAE Naltrexone Registry Check: What Is Actually Listed?
A dated check of the UAE drug directory: Contrave is active, standalone naltrexone was not found, and DHA guidance still recognises naltrexone clinically.
2 minute read
Treatment Evidence
Naltrexone vs Acamprosate and Disulfiram
Naltrexone, acamprosate, and disulfiram have different goals, contraindications, and evidence. There is no universal best medicine.
3 minute read
Treatment Evidence
Does Naltrexone Help With Weight Loss? Contrave Evidence
Standalone naltrexone is not an approved weight-management medicine. This evidence review examines Contrave—the naltrexone-bupropion combination—alongside its safety limits.
4 minute read
Treatment Evidence
Targeted Naltrexone in Asia-Pacific: What Access Evidence Shows
Targeted naltrexone has trial evidence, but local access depends first on whether standalone naltrexone is marketed and whether a clinician supports the protocol.
3 minute read