PBS oral product
Naltrexone treatment information
Get Naltrexone
Evidence-led information about naltrexone in care for alcohol use disorder and opioid use disorder. Country guides separate clinical evidence, product status, funding, and access across eight health systems.
Naltrexone evidence by country
A clinical use, registered product, public funding, and pharmacy supply are different facts. Choose a country to see what current sources confirm.
Coverage varies
Canada
PHARMAC oral product
New Zealand
Contrave confirmed
Singapore
Two products listed
South Africa
Contrave confirmed
United Arab Emirates
Specialist pathway
United Kingdom
Oral and XR products
United States
Naltrexone at a glance
Useful orientation—not a promise of individual treatment results or local supply.
- Country evidence guides
- 8
- Common oral strength
- 50 mg
- US monthly injection
- 380 mg
- Established uses
- 2
Regulation, funding, product, and pathway checks
Standalone tablets used in many substance-use treatment protocols
Extended-release Vivitrol dose administered by a clinician
Alcohol use disorder and prevention of relapse to opioid use
What you will find on this site
The hub is organized around four evidence questions.
What does the medicine do?
Learn the pharmacology, approved uses, safety constraints, and limits of the clinical evidence—including the Sinclair Method, Contrave, and low-dose naltrexone.
What exists in this country?
Country guides check official labels, medicine registers, formularies, funding schedules, and treatment guidance without assuming regional availability.
What will still vary locally?
Coverage, pharmacy stock, clinician fees, eligibility, and individual suitability can change. Each guide identifies where local confirmation is still needed.
Where is the evidence?
Articles lead with a direct answer and key takeaways, then link to primary regulatory, payer, guideline, and clinical sources.
Latest treatment guides
In-depth articles about naltrexone treatment across the countries we cover.
Treatment & Safety
Naltrexone Contraindications: Opioids, Withdrawal, and Label Checks
Current opioid use, opioid dependence, acute withdrawal, specified test results, and prior hypersensitivity can make naltrexone unsafe to start.
4 minute read
Treatment & Safety
Starting Naltrexone After Opioids: Why the Opioid-Free Interval Matters
Naltrexone can trigger severe withdrawal if opioids are still present. The minimum interval is not a self-assessment rule and may be longer after buprenorphine or methadone.
4 minute read
Treatment & Safety
Naltrexone Side Effects: Expected Effects and Urgent Safety Signals
Nausea, headache, dizziness, and tiredness are reported with naltrexone. Vivitrol also has injection-site effects; certain symptoms need prompt clinical review.
3 minute read
Check naltrexone evidence where you live
Product status, funding, supply, and prescribing pathways differ. Choose a country to see the dated evidence and the questions that still need local confirmation.